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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RRN3
All Species:
23.94
Human Site:
S218
Identified Species:
43.89
UniProt:
Q9NYV6
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NYV6
NP_060897.3
651
74107
S218
K
F
P
F
V
R
K
S
E
R
T
L
E
C
Y
Chimpanzee
Pan troglodytes
XP_001143837
595
67943
D199
I
E
K
L
L
K
L
D
V
N
A
S
R
Q
G
Rhesus Macaque
Macaca mulatta
XP_001108222
651
74080
S218
K
F
P
F
V
Q
K
S
E
R
T
L
E
C
Y
Dog
Lupus familis
XP_536965
651
74211
S218
K
F
P
F
V
R
K
S
E
R
T
L
E
C
Y
Cat
Felis silvestris
Mouse
Mus musculus
B2RS91
656
74499
S216
K
F
P
F
V
R
K
S
E
R
T
L
E
C
Y
Rat
Rattus norvegicus
NP_001129318
661
75125
S216
K
F
P
F
V
R
K
S
E
R
T
L
E
C
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518561
660
75690
S227
K
F
P
F
I
T
K
S
E
R
T
L
E
C
Y
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001107876
612
69642
Y202
N
L
L
R
I
T
V
Y
F
P
T
L
R
L
E
Zebra Danio
Brachydanio rerio
XP_706962
612
68744
Y202
N
L
L
R
V
T
V
Y
I
P
D
L
R
K
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_788084
611
70731
P201
K
F
P
Y
F
K
K
P
Y
H
V
T
A
G
Y
Honey Bee
Apis mellifera
XP_001122533
483
56793
C89
A
F
I
E
D
L
I
C
M
Q
I
H
Y
A
K
Nematode Worm
Caenorhab. elegans
P48322
654
75091
P205
V
M
P
H
F
T
R
P
S
V
T
V
A
G
Y
Sea Urchin
Strong. purpuratus
XP_784172
374
42533
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.4
97.6
90.6
N.A.
86.8
85.4
N.A.
76
N.A.
66.8
59.9
N.A.
29.7
27.7
24.4
28.5
Protein Similarity:
100
89
99
94.7
N.A.
92.9
91.8
N.A.
86
N.A.
79.8
76
N.A.
48.8
46.3
42.8
40.7
P-Site Identity:
100
0
93.3
100
N.A.
100
100
N.A.
86.6
N.A.
13.3
13.3
N.A.
33.3
6.6
20
0
P-Site Similarity:
100
13.3
100
100
N.A.
100
100
N.A.
93.3
N.A.
20
13.3
N.A.
46.6
13.3
33.3
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
0
0
0
0
8
0
16
8
0
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
0
0
0
47
0
% C
% Asp:
0
0
0
0
8
0
0
8
0
0
8
0
0
0
8
% D
% Glu:
0
8
0
8
0
0
0
0
47
0
0
0
47
0
8
% E
% Phe:
0
62
0
47
16
0
0
0
8
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
16
8
% G
% His:
0
0
0
8
0
0
0
0
0
8
0
8
0
0
0
% H
% Ile:
8
0
8
0
16
0
8
0
8
0
8
0
0
0
0
% I
% Lys:
54
0
8
0
0
16
54
0
0
0
0
0
0
8
8
% K
% Leu:
0
16
16
8
8
8
8
0
0
0
0
62
0
8
0
% L
% Met:
0
8
0
0
0
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
16
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% N
% Pro:
0
0
62
0
0
0
0
16
0
16
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
8
0
0
0
8
0
0
0
8
0
% Q
% Arg:
0
0
0
16
0
31
8
0
0
47
0
0
24
0
0
% R
% Ser:
0
0
0
0
0
0
0
47
8
0
0
8
0
0
0
% S
% Thr:
0
0
0
0
0
31
0
0
0
0
62
8
0
0
0
% T
% Val:
8
0
0
0
47
0
16
0
8
8
8
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
16
8
0
0
0
8
0
62
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _